Epidermoid cyst: Also known as sebaceous cyst, epidermoid inclusion cyst, Infundibular cyst, epidermal cyst. It is a benign walled-off cavity filled with keratin which originates from the hair follicle unit. Clinical appearance: Skin-coloured to yellow-white unless inflamed. The size varies from several millimetres to centimetres. A visible comedonal-like opening or pore (resembles a blackhead) may […]
What is solar lentigo? Solar lentigo is a harmless patch of darkened skin. It results from exposure to ultraviolet (UV) radiation, which causes local proliferation of melanocytes and accumulation of melanin within the skin cells (keratinocytes). Solar lentigos or lentigines are very common, especially in people over the age of 40 years. Sometimes they are also known as an “old age spot” […]
Neurofibroma: Relatively common benign peripheral nerve sheath tumour composed of a mixed population of Schwann cells, fibroblasts, and perineurial or perineurial-like cells, with scattered intermingled axons. It is most often a sporadic tumour, but it can also occur as manifestation of the genetic syndrome Neurofibromatosis (NF1). Neurofibromas may assume one of three growth patterns: localized, […]
Glomus tumors are rare soft tissue neoplasms that typically present in adults (ages 20-40 years) as small, blue-red papules or nodules of the distal extremities, with most cases involving subungual sites. These tumors are typically painful, often causing paroxysmal pain in response to temperature changes or pressure. (See Figures 1 & 2)
Glomus tumors are thought to arise from the glomus body, a thermoregulatory shunt concentrated in the fingers and toes. Most lesions are solitary and localized to cutaneous sites; however, generalized glomuvenous malformations, or multiple glomangiomas, have also been described, and may have extracutaneous involvement.
While the vast majority of glomus tumors are benign, malignant cases have been rarely reported, with such cases typically being locally invasive, and with metastases being exceedingly rare.
Background A poroma is a benign adnexal neoplasm composed of epithelial cells that show tubular (usually distal ductal) differentiation. The malignant counterpart of a poroma is referred to as porocarcinoma.] Poromas historically have been considered glandular adnexal neoplasms of eccrine lineage, and this view is so entrenched that the neoplasm is often referred to as […]
Tinea pedis is a foot infection due to a dermatophyte fungus. Tinea pedis thrives in warm humid conditions and is most common in young adult men. Tinea pedis is most frequently due to: Trichophyton (T.) rubrum T. interdigitale, previously called T. mentagrophytes var. interdigitale Epidermophyton floccosum Moccasin tinea pedis Clinical features Tinea pedis has various patterns and may […]
What is tuberous sclerosis? Tuberous sclerosis or tuberous sclerosis complex (TSC) is a genetic disorder that is characterised by hamartomas in many organs, but particularly the skin, brain, eye, kidney and heart. Hamartomas are non-cancerous malformations composed of overgrowth of the cells and tissues that normally occur in the affected area and include naevi (birthmarks). […]