Squamous Cell Carcinoma in situ (Bowen’s Disease)
Squamous cell carcinoma (SCC) in situ, also known as Bowen disease, is SCC confined to the epidermis and superficial adnexal epithelium, further characterised by full-thickness involvement of the epidermis by dysplastic squamous cells. The term "Bowen disease" was originally used specifically to describe SCC in-situ in sun-protected skin as a harbinger of internal malignancy, but the terms "Bowen disease" and "SCC in situ" are now used interchangeably to describe epidermal SCC in situ of both sun-dam-aged and sun-protected skin.